I have been discussing this with a number of colleagues and I am running into a lack of research in the area likely due to the rarity of hereditary Transthyretin amyloidosis and GBS. There are no case reports of patients with both of these conditions. Below is an article regarding CSF TTR concentrations in patients with GBS.
I cannot seem to find any research regarding CSF levels of TTR in patients with hATTR. I am curious as to whether this transient increase in TTR may affect patients with hATTR differently. Could this exacerbate hATTR? Could it alter the severity of GBS symptoms? I would greatly appreciate any opinions on the matter.
Note: I am a medical student and this is not a personal medical question. This is a question that was brought up during a clerkship and we did not come to any conclusions on the matter. I am interested in gathering more opinions and learning what others might think about this.
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